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Breast cancer patients under 45 years of age using tissue microarray technique Role of immunohistochemical biomarkers

Breast cancer patients under 45 years of age using tissue microarray technique Role of immunohistochemical biomarkers Purpose: Tissue microarray (TMA) is used for the paraffin block of tumor tissue in patients under 45 years of age. Expression status of five biomarkers such as estrogen receptor (ER), progesterone receptor (PR), HER-2, COX-2 and Survivin And to investigate the significance as a prognostic factor in patients. Materials and Methods: From March 1994 to August 2005, TMA analysis was performed among breast cancer patients under 45 years of age A total of 212 patients were enrolled. The age of the patients ranged from 23 to 45 years and the median age was 39 years. The probing period was 24 months and the median follow - up period was 60 months. After selecting a patient under 45 years of age, After marking the cancerous area through the dyed slides, a microstructure array was made through a TMA instrument. And five living bodies Immunohistochemical staining of...

We finish the summer season and prepare summer houses, gardens and vegetable gardens for winter. The cold season is not far away.

We finish the summer season and prepare summer houses, gardens and vegetable gardens for winter. The cold season is not far away. And we all puzzled at the question from all angles: the work to collect good harvests again next year and enjoy a healthy garden, how to prepare for a holiday or winter getaway for winter, protecting from frosty fruits, berries and ornamental plants performed in empty beds Garden crops? Of course, each site needs a separate approach. But there are general rules to follow so you can enjoy the performance of labor next year. It is a recommendation we have collected in the issue of this magazine. Preparing to do all the work in a day, you can not do most, but your hard work today, the bigger your site is safe, the more likely it will survive the long winter. For some, the site is a resting place, but it is primarily a breadwinner for many of us. In our interests, it is necessary to prepare frost and frost in climatic conditions, not only in spring ...